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Emerging Diseases

The SARS-CoV-2 virus

Coronaviruses are a large family of viruses, which cause diseases ranging from the common cold (some seasonal viruses are Coronaviruses) to more severe diseases such as MERS-COV or SARS.

The virus identified in January 2020 in China is a new Coronavirus, named SARS-CoV-2. The disease caused by this coronavirus has been named COVID-19 by the World Health Organization – WHO. Since March 11, 2020, the WHO calls the global situation of COVID-19 a pandemic; i.e. the epidemic is now global.

The Ebola virus

Ebola virus disease (formerly known as Ebola haemorrhagic fever) is a serious, often fatal disease in humans. The virus is transmitted to humans from wild animals and then spreads to people through human-to-human transmission. The first outbreaks of Ebola disease occurred in remote villages in central Africa, close to tropical forests, but the recent outbreak in West Africa affected large urban centres as well as rural areas.

The average case-fatality rate is about 50%. In previous outbreaks, rates have ranged from 25% to 90%. Community participation is essential to contain outbreaks. To be effective, control must be based on a combination of interventions: case management, surveillance and contact tracing, quality laboratory services, safe burials and social mobilization. Early supportive care focusing on rehydration and symptomatic treatment improves survival rates.

No approved treatment has yet been shown to neutralize the virus, but several treatments (blood derivatives, immunologic or drug therapies) are being investigated. There is currently no licensed vaccine against Ebola disease, but two candidates are being evaluated.

Solthis Action

Health workers were hit hard by the outbreak of Ebola disease in West Africa, working tirelessly to care for the sick and risking their lives every time they went to work. According to a WHO report on infection among health workers, the risk of Ebola infection is between 21 and 32 times greater for health workers than for the general population.

Solthis has therefore committed to its local and international partners to support the new measures to protect healthcare workers and patients in line with the national Ebola response plans in these two countries by providing training for healthcare workers, technical assistance to check the availability of protective equipment in HIV units and monitoring the implementation of prevention measures in the HIV units of the sites targeted by the project.

 

Country action

GUINEASIERRA LEONENIGERMALI

Expertise

OPERATIONAL RESEARCHHEALTH INFORMATION SYSTEMCAPACITY BUILDINGSTRENGTHENING SYSTEMS AND HEALTH SERVICESHUMAN RESOURCES FOR HEALTHHEALTH PRODUCTS AND PHARMACEUTICAL SYSTEMLABORATORIES AND TECHNICAL PLATFORMSHEALTH FINANCINGGOVERNANCE AND HEALTH POLICIESADVOCACY

Health priority

HIV / AIDSTUBERCULOSISHEPATITIS

Associated contents

JIKI TRIAL – Favipiravir Ebola Guinea – Publication in PLOSmedicine

2016 |  Research papers

GUINEAOPERATIONAL RESEARCHEmerging Diseases

The INSERM and other partners of the JIKI trial, among which Alima, Doctors w/borders, the Red Cross published a research paper in PLOSmedicine : see this publication  The JIKI clinical trial seeked to test the effectiveness of Favirapir among people infected with the Ebola virus in Guinea. Solthis is pleased to have been able to participate in a modest degree to this project by facilitating the achievement of this trial on the spot through its team based in Conakry.

  Download resources

CROI 2016 : Access to HIV care in the health districts affected by the Ebola outbreak in Sierra Leone

2016 |  Posters

SIERRA LEONEOPERATIONAL RESEARCHHEALTH INFORMATION SYSTEMHIV / AIDSEmerging Diseases

Presentation of the poster “access to HIV care in the health districts affected by the Ebola outbreak in Sierra Leone” for the CROI 2016. Download the poster Jacques CROI 2016 Official Website : CROI 2016

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CROI 2015: Solthis and Donka National Hospital Poster

2015 |  Posters

OPERATIONAL RESEARCHHIV / AIDSEmerging Diseases

Presentation of Solthis and Donka National Hospital poster on the 'impact of the Ebola outbreak on the quality of care of people living with HIV taking antiretroviral treatment at Donka National Hospital in Conakry, Guinea' More informations about CROI 2015

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THE LANCET : Prevention of HIV spread during the Ebola outbreak in Guinea

2015 |  Scientific Papers

GUINEAOPERATIONAL RESEARCHHIV / AIDSEmerging Diseases

Author(s): J. NDawinz, M. Cissé, M. SK Diallo, C. T. Sidibé and E. D'Ortenzio Journal: The Lancet, April 11, 2015

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